Game 5 arrives in Detroit with availability concerns taking center stage. The Pistons enter a pivotal home matchup monitoring several rotation pieces. At the same time, the Cavaliers head into the game fully healthy and looking to push the series lead for the first time.

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This is bigger than winning a playoff series. The outcome of this tie will make-or-break the future of these franchises. With the biggest game of the series set for tonight, let’s preview the possible injury concerns for the clash.

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Detroit Pistons vs Cleveland Cavaliers Game 5: injury report

Detroit Pistons

Detroit enters Game 5 already dealing with rotation uncertainty, with Kevin Huerter (left abductor strain, trending in the right direction) and Duncan Robinson (low back soreness, 43.6% from beyond the arc in the playoffs) both listed as questionable, potentially thinning Detroit’s perimeter options.

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Caris LeVert is also questionable with a right heel contusion, compounding the Pistons’ depth issues as they head into a crucial home matchup.

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Cleveland Cavaliers

Kenny Atkinson can have a peaceful sleep the night before Game 5. The Cleveland Cavaliers’ stock is on the rise after claiming back-to-back wins at home. Not only have Donovan Mitchell and James Harden looked reinvigorated, but the Cavs have zero injury concerns heading into the pivotal game on the road.

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Detroit Pistons vs Cleveland Cavaliers Game 5: Predicted starting lineup

Detroit Pistons  Cleveland Cavaliers 
Cade Cunningham James Harden
Duncan Robinson* Donovan Mitchell
Ausar Thompson Max Strus
Tobias Harris Evan Mobley
Jalen Duren Jarrett Allen

Detroit Pistons vs Cleveland Cavaliers Game 5: Odds

Despite the possible toll injuries could have on the Pistons, they are seen as small favorites for Game 5. The moneyline is set at -166, while the Cavaliers are at +1140. Considering the home-road scenario, these odds are close. There’s a pattern in this series in which the Pistons’ status as favorites remains unchanged. Neither team has won a game on the road yet. But the Cavaliers have a great chance to break their curse and claim their first road win in this postseason.

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Detroit Pistons vs Cleveland Cavaliers Game 5: Where to watch

Date: Wednesday, May 13, 2026
Location: Little Caesars Arena, Detroit, Michigan
Time: 8:00 P.M. E.T.
TV: ESPN
Streaming: ESPN app

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