The Buffalo Bills are one of the favorites to win Super Bowl LX, yet their road to glory has never looked tougher. After defeating the Jacksonville Jaguars and breaking the shackles of their playoff on-road win, Josh Allen and co will have to face the no. 1 seed in the AFC during the NFL Divisional Round on Saturday.

“Just announced: The NFL Divisional Round schedule: Saturday: – 4:30 ET: Bills @ Broncos ON CBS,” posted Ari Meirov on X.

The Bills will have to be in the best shape if they want to overcome the Denver Broncos. The Broncos have a home-ground advantage, which will make the situation more challenging for the Bills. They just got their first playoff on-road win in the Josh Allen-Sean McDermott era. Now, in the following week, they will participate in another on-road game.

The Broncos have been rallying around quarterback Bo Nix, who has been excellent this season. His box score reads 63.4% pass completion rate for 3,931 passing yards and 25 touchdowns. His running game is also impressive, covering 356 yards and five touchdowns in 83 carries. Linebacker Nik Bonitto has been great on defense. He has made 14 sacks this season, along with two forced fumbles. Bonitto could be a problem for Allen, especially since Allen has been sacked 40 times this season already.

It will be a game of offense vs. defense. The Broncos have allowed an average of 18.3 points, while the Bills have scored 28.3 points on average. The former’s offense averages 376.3 yards per game, while the latter allows 278.2 yards per game. Similarly, the Bills allowed 21.5 points per game, and the Broncos scored an average of 23.6 points each game. Amid the differences in stats, the Broncos are not the only ones who can hamper the Bills’ dream of lifting the Lombardi Trophy. The franchise’s IR can also play a massive role in this regard.

The Buffalo Bills have a long list of injuries lined up

Before the Bills entered EverBank Stadium, there was a lingering question about whether Josh Allen would play or not. Despite HC McDermott announcing Allen was suffering from soreness, he did play against the Jaguars. While he seems to have recovered, there are other names on the Bills’ IR, which could be a problem for them.

Tight end Dalton Kincaid’s status remains questionable ahead of the AFC Divisional Round. He played against the Jaguars, scoring a receiving touchdown. But he has not fully recovered from his knee injury. Following the 27-24 victory over the Jaguars, he was seen wearing a walking boot. Fortunately, he will be available for the weekly practice.

Wide receiver Tyrell Shavers suffered a knee injury against the Jaguars and is still being evaluated. It remains to be seen whether he will be available against the Broncos. Unlike Shavers, WR Gabe Davis (torn ACL) and safety Jordan Poyer (hamstring) have been confirmed to be out.

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Amid all the injuries, the Bills do have some good news. LB Terrel Bernard, CB Maxwell Hairston, and RB Ty Johnson are all improving. DT Ed Oliver and WR Curtis Samuel are open to returning to practice. On top of everything, Josh Allen is confirmed to play the game despite suffering from soreness.

The road ahead is tough, but if anything, the Bills have always shown they can overcome any adversities. Can the Bills continue their playoff on-road win streak, or will they fall prey to the no. 1 seed? It remains to be seen what script will be written on Saturday at 4:30 PM ET at Empower Field at Mile High.