Kyle Shanahan-coached San Francisco 49ers started their 2021 NFL campaign on a positive note. The 49ers are without a defeat in their opening games with Jimmy Garoppolo as their starter. However, they will face a tough challenge when they host Aaron Rodgers and the Green Bay Packers at the Levi’s Stadium on Sunday.

Meanwhile, the Packers registered a convincing 17-35 win over divisional rivals Detroit Lions last weekend. They will look to continue in the same vein when they go on the road to San Francisco in Week 3.

Here’s a detailed look at both teams, along with injury updates and Week 3 Matchday predictions.

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San Francisco 49ers look to continue winning run in Week 3

Despite the arrival of rookie Trey Lance in the summer, San Francisco 49ers HC Kyle Shanahan has backed Jimmy Garoppolo as starter in the build-up to Week 3 of the ongoing 2021 NFL season. The 49ers registered back-to-back wins over Lions and the Philadelphia Eagles.

Jimmy G has repaid that faith up until now, throwing for 503 yards with 2 passing touchdowns in 2 games. Unlike last year, the 49ers have a fully-fit squad to choose from (barring Raheem Mostert). Expect the likes of George Kittle and others to trouble the Packers’ defense in front of home fans in the Bay.

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Green Bay Packers eager to put behind disappointing Week 1 loss

After a disappointing opening week loss to New Orleans Saints, Aaron Rodgers and the Green Bay Packers bounced back in Week 2 against Detroit. The reigning NFL MVP threw for 255 yards with 4 passing touchdowns last weekend. He will look to link up with Robert Tonyan and Davante Adams once again in Week 3.

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San Francisco – Out

DT Kevin Givens – Ankle

RB JaMycal Hasty – Ankle

Questionable

DE Arik Armstead – Adductor

DT Javon Kinlaw – Knee

CB Emmanuel Moseley – Knee

Doubtful

RB Elijah Mitchell – Shoulder

Green Bay – Out

G Elgton Jenkins – Ankle

TE Dominique Dafney – Hip

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49ers vs Packers Prediction

San Francisco 49ers 23 – 33 Green Bay Packers

This game is a rematch of the 2019 NFC Championship game which the 49ers eventually won. Knowing Aaron Rodgers and how he feels about losses, that defeat will still be fresh in his mind.

That should be motivation enough for the California-born veteran to put on a stellar display on the road. Can the Packers get vengeance for their 2019 heartbreak? Guess we’ll find out soon enough.