Sean Payton’s New Orleans Saints are probably the hottest team in the NFL right now (apart from the Pittsburgh Steelers, of course). They are currently on a 5-game winning streak, having last lost to the Green Bay Packers in Week 5.

Meanwhile, Kyle Shanahan’s San Francisco 49ers sit at the bottom of the NFC West Division table with 4 wins from 9 games. They are currently on a 2-game losing streak and will hope to extend that when they travel to the Mercedes-Benz Superdome on Sunday.

Here’s a detailed look at both teams, along with injury updates and Week 10 Game Day predictions.

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New Orleans Saints looking to build some momentum heading into a crucial phase

The Saints have been terrific over the last couple of weeks. They have been boosted by the return of talented wide receiver Michael Thomas. They made their way to a commanding 3-38 win over divisional rivals Tampa Bay Buccaneers last weekend.

Coach Sean Payton will be delighted with how his team has performed after a slow start to the season. Quarterback Drew Brees and RB Alvin Kamara will be key for the home team if they want to beat the 49ers.

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Second-string QB Taysom Hill will also be an important asset for the Saints in Week 10.

Can Kyle Shanahan’s San Francisco 49ers pull off a surprise win on Sunday?

The 2020 NFL season is turning out to be a nightmare for Kyle Shanahan and the San Francisco 49ers. They have been dealt with massive injury blows this year. The likes of Jimmy Garoppolo, Nick Bosa, George Kittle, and Raheem Mostert are all ruled out for Sunday’s clash against the Saints.

The Niners will once again play with Nick Mullens as their starter. WR Deebo Samuel and RB Tevin Coleman have also been sidelined for tomorrow’s game at the Mercedes-Benz Superdome. The 49ers will need a miracle to win this one.

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NFL Preview: New Orleans Saints vs San Francisco 49ers Injury Updates

New Orleans – Questionable

RB Dwayne Washington – Back

San Francisco – Out

RB Tevin Coleman – Knee

WR Deebo Samuel – Hamstring

CB K’Waun Williams – Ankle

LB Demetrius Flannigan-Fowles – Hamstring

Questionable

WR Trent Taylor- Back

WR River Cracraft – Quadricep

Saints vs 49ers Prediction

New Orleans Saints 33 – 14 San Francisco 49ers

Once again, as has been the trend all season, the San Francisco 49ers have been hit with additional injuries ahead of their weekly fixture. The Drew Brees-led New Orleans Saints will undoubtedly be the favorites heading into this tie.

While the Niners are forced to bench their top players, the Saints are welcoming some new stars to the line-up. Two former Red and Gold players, Emmanuel Sanders and Kwon Alexander are in line to feature for New Orleans on Sunday. Who will have the last laugh, Kyle Shanahan or Sean Payton? Tune in to find out.

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