Centre back Ramos having hurt his troublesome shoulder while scoring in Real Madrid's 3-2 defeat at Sevilla, and fullback Juanfran having sustained a thigh strain, both of them have withdrawn from the squad for this month's friendlies against England and Belgium.
Manager Claudio Ranieri has hailed Leicester City's team spirit after Riyad Mahrez stepped aside for Jamie Vardy to score from the spot in the Watford win.
Arsenal's Olivier Giroud missed a flurry of chances against Tottenham but manager Arsene Wenger was satisfied to see his frustration with his performance.
Jesse Lingard's first senior Manchester United goal in the 2-0 Premier League win over West Bromwich Albion has given the winger the confidence and belief.
After a six-match unbeaten start to his reign as Liverpool manager Jurgen Klopp came down to earth as his side lost to Crystal Palace in the Premier League.